Innovation in Implantable Stimulators

OUROBOROS

A multi-purpose implantable stimulator with infinite waveforms



What is the significance of infinite waveforms for the brain? The answer to this question lies in the history and technology of brain stimulation and the science of deep brain stimulation.   In the ‘60’s  Dr. Jose Delgado, a neuroscientist, stimulated the deeper parts of the brain. He discovered that the deep parts of the brain were the control box of the brain and body. His most famous experiment was stopping a charging bull by remote control deep brain stimulation.

Jose Delgado stopping a charging bull by

remote controlled brain stimulation

 

Picking up on Delgado’s work, it was discovered that stimulating a specific part of the deep brain, the subthalamic nucleus, halted the tremors and rigidity of Parkinson. This was tried on humans with tremendous success. People who's bodies' shook terribly turned as calm as a pond on a breezeless day with a flick of a switch. People who were paralyzed by muscle rigidity were up, running and dancing immediately. It was nothing short of a miracle.

Yet deep brain stimulation (DBS) surgery for the reduction of Parkinson disease is not perfected. Currently DBS surgery is in two steps. First the patient must be implanted with electrodes in the brain. Afterwards, the patient undergoes another surgery to place a bulky stimulators in the chest and connecting it to the electrodes in the brain. After the two surgeries, the patient has to undergo a period of “programming” sessions. During these sessions, a nurse literally fumbles with dials to find the best stimulator settings so that the patient stop shakings, feels “well” enough without any unpleasant side effects.

The problem is in the hardware. The same bulky pacemakers that control the rhythm of the heart are used in stimulating the brain without a single modification. Only FDA approved devices can be implanted in the human body and the heart pacemakers were the only FDA approved devices at the time.

Biotele's Ouroboros is an improvement on the old pacemaker. It is smaller, fits easily in the body and can generate infinite waveforms.

 

Biotele's Ouroboros System

The fundamental function of Biotele's Ouroboros is the ability to record infinite types of waveforms to memory and play them back. This function is important because unlike the heart, the brain is a signal processing system. The heart might be satisfied with a monotonous rhythm, but the brain requires more complicated waveforms. The recorded waveforms are tailored for the patient's brain, unlike the old pacemakers that only had factory preset waveforms. The tailored waveforms give the optimal stimulation with the lest side effects resulting in the best possible patient relief. Furthermore, the stimulator can fit inside the head saving the patient an extra surgery.


Biotele's Ouroboros' topology


 

Since Biotele's Ouroboros is small and with infinite types of waveforms, it can be used for many different ailments other than Parkinson. It can also act as a signal relay. For example, a cut spinal cord, like that of a quadriplegic, can be virtually mended.  In places were the nerve signals are severed, commands that normally flow from the brain to the limbs are recorded at the brain then and played back to the nerves beyond the severed part.

 

Clinical Uses for Biotele's Ouroboros

 

 

 
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SYSTEM AND METHOD FOR PROVIDING A WAVEFORM FOR STIMULATING BIOLOGICAL TISSUE


US Patent Office Application


European Patent Office Application

Implant Sites for Ouroboros


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